Answer 2:
There are two answers to this question: proximate (i.e., short-term) and ultimate (i.e.,
long-term). The proximate origin of cells is, of
course, other cells. Most cells reproduce
asexually through cell division, which is called binary fission in prokaryotes and mitosis in eukaryotes (with the exception of sex cells or gametes that form through meiosis). However, some cells, notably bacteria and other prokaryotes are able to borrow parts of each others DNA or RNA in a process more akin to sexual reproduction.
Prokaryotes are more primitive cells that do not have a nucleus to enclose their genome and do not have membrane-bound organelles, whereas eukaryotes contain their genome (DNA orRNA) within a nucleus and have membrane-bound organelles.
The ultimate origin of cells is a much more difficult question and involves the actual evolution of cells from the elements and molecules that occurred on Earth hundreds of millions of years ago. Cells are essentially just self-replicating bundles of ribonucleic acids (RNA or DNA) that are enclosed in a semi-permeable membrane. There is quite a bit of experimental evidence to show that certain types of molecules called phospholipids automatically assemble into spherical membranes when exposed to an aqueous environment (thephospholipids have a water-attracting hydrophilic end that points outwards and a water-repellant hydrophobic end that points inwards). Likewise, other types of molecules called nucleic acids are capable of making copies of themselves by polymerizing nucleotides. At some point in time, phospholipids membranes enclosed nucleic acids, forming a primitive cell.
The phospholipid membrane must have been permeable to the nucleotides that nucleic acids are composed of, or the cell must have had some means to assemble nucleotides from basic molecules or elements that could penetrate the membrane. The nucleic acids then began to duplicate themselves by polymerizing nucleotides. Then, the
phospholipid membrane must have increased in size
until it was no longer stable and split into two
smaller membranes (binary fission), each
containing replicate nucleic acids.
From here, different cells adapted or evolved to perform specialized functions by producing or
incorporating new molecules into their body. At
some point, the nucleic acids began to code for
the production of amino acids and their
polymerization into proteins, such as enzymes.
These proteins then became involved in carrying
out important biochemical reactions. For
instance, some of these enzymes may have assisted
in transporting necessary elements or molecules
through the membrane (e.g., via endocytosis) to assist the replication of the nucleic acids or the production of new proteins. Others may have been responsible for isolating and excreting waste materials from the cell (e.g., via exocytosis). Others may have assisted in translating nucleic acids into proteins, packaging and folding the proteins so that they function correctly, or breaking down and recycling used or defective proteins. Mutations in the nucleotide sequence of nucleic acids would cause changes in these proteins that are produced, and these changes, if adaptive, would eventually lead to the evolution of new cell types.
Finally, some prokaryotic cells were engulfed but not digested by other cells (probably amoeboid-like eukaryotes), were incorporated into the larger cells body, and then co-opted to carry out novel functions. For instance mitochondrion and chloroplasts are organelles that have their own double phospholipid membranes and separate genomes from their parent cells. Some scientists believe that mitochondria and chloroplasts were independent prokaryotic cells many millions of years ago, but at some point were incorporated into eukaryotes and used by their new host cells for oxidative phosphoryltation and photosynthesis, respectively. This is called the Theory of Endosymbiosis. Click Here to return to the search form.
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