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What is the importance of the number of Adenine nucleotides in the poly-A tail once pre-mRNA is converted to mRNA?
Answer 1:

The poly-A tail stimulates re initiation of translation by the ribosome sub units. I think there is an optimum size range (~100 - 250 bases), but within that range the specific length is not critical. There are species-related variations in the optimal tail length range.



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