Answer 1:
First of all, I want to remind you that Sickle
cell disease is an inherited blood disorder that
affects red blood cells.
I searched for
information on your question. According to what I
found, it is possible to get Sickle cell disease
even if you are not African American. Sickle cell
disease is quite variable in itself. Researchers
know of only a few of the factors that contribute
to this variability. Some are genetic. Others
likely involve environmental influences. One of
the most important genetic factors is thalassemia.
One form of thalassemia, called -thalassemia,
reduces the production of normal hemoglobin. A
person with one normal hemoglobin gene and one
thalassemia gene has thalassemia trait (also
called thalassemia minor). Should one parent have
sickle cell trait and the other have thalassemia
trait, any child they conceive has one chance in
four of receiving one gene for sickle cell disease
and one gene for β-thalassemia . This condition is
called sickle β-thalassemia. The severity varies.
Some patients with sickle β-thalassemia have a
condition as severe as sickle cell disease itself.
Others have few and relatively mild problems. The
gene for thalassemia is very common among people
of Mediterranean origin. The sickle gene also
exists in people of Mediterranean origin, although
its frequency is much lower than that for
thalassemia. People of, say, Greek or Italian
background who have a sickle condition most often
have sickle β-thalassemia.
The Sickle cell
disease is an inherited condition; the disease
comes with the newborn. Two genes for the sickle
hemoglobin must be inherited from one's parents in
order to have the disease. A one-in-four chance
(25%) exists that a child will inherit two normal
genes from the parents. A one-in-four chance (25%)
also exists that a child will inherit two sickle
cell genes, and has Sickle cell disease. A
one-in-two chance (50%) exists that the child will
inherit a normal gene from one parent and a sickle
gene from the other. This would produce Sickle
cell trait. Sickle cell trait produces no symptoms
or problems for most people. Sickle cell disease
can neither be contracted nor passed on to another
person.
Here is the interesting web site
where I got most of this information:
sickle_cell_d Click Here to return to the search form.
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