Not all spiders are dangerous to humans. The spider usually injects its prey with venom kill the spider's prey, but because humans are a lot bigger than the prey that these spiders like to hunt, most spider venom usually doesn't kill (or even leave a noticeable mark) on a human unless the venom is especially strong. There are actually only a few spider species in the United States that would really hurt a person -- Here's a great visual list of common poisonous spiders: spider-identification
Spider poisons usually have proteins that destroy cells through different mechanisms. Often times these poisons target specific functions or areas in the body, such as the nervous system. Hope that helps!
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