Yes, it is possible. All you need is to deposit a
chiral substance on the surface of the particles
that build up your thin layer. Any time a racemic
mixture (the mixture of two enantiomers) interacts
with a surface that is chiral, one of the
enantiomers is going to be attracted more strongly
to that surface than the other, and that is the
basis for chromatographic separation.
would like a deep insight into the what has been
done by this technique, you can ask your librarian
for a copy of the paper:Abdoul-Enein, H. Y.;
El-Awady, M. I.; Heard, C. M., Nicholls, P.
J.Applications of thin-layer chromatography in
enantiomeric chiral analysis - an overview
Biomedical Chromatography, vol. 13, 531-537, 1999I
hope this is enough, otherwise, let me know!
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