Answer 2:
Chickenpox is caused by the varicella zoster virus. Upon infection, the virus will spread in the blood stream. This is called viremia, the presence of virus in the blood. The blood stream will carry the virus around the body. The virus will settle in the nerves of the host. In fact, almost all patients recovered from a chickenpox infection have the virus in their trigeminal ganglia, the two clusters of nerves behinds each of your check bone, throughout their lives. They have those little friends with them forever!
This is somewhat beneficial as the virus replicates in small numbers and reinforces the immune system's memory. If the immune system holds up, this provides people life-long immunity to the virus. However, in some cases, the immune system fails to suppress the virus and this leads to shingles. This happens in older people as their immune system is not as strong as it was. Shingles manifest as painful blisters in a strip of skin. It turned out that the particular strip of skin, a dermatome, is supplied by a particular nerve.
There are two kinds of vaccine for the varicella zoster virus, one for chickenpox, another for shingles.
The chickenpox vaccine uses attenuated virus. This means that the virus is alive but a strain that cannot cause as severe a disease as the wild type. As a consequence, the attenuated virus can only spread in the dermatome it arrived in. People with the vaccine indeed can develop shingles, however it is **much less likely** comparing those that were infected with the wild type virus.
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